Lost on or after 04 MAY 1945 with the loss of 86 officers and men near the Gulf of Siam on her second war patrol.
USS BAYA tried to contact USS LAGARTO and she made no reply. Japanese records state that during the night of 3-4 May, mine layer HATSUTAKA attacked a U.S. submarine in that location. It is presumed that USS LAGARTO perished with all hands in this battle.
The Japanese minelayer HATSUTAKA was sunk by the USS HAWKBILL (SS 366) two weeks later.